Targeting Tumor Microenvironment in Breast Cancer
Discover how the evolving science of the tumor microenvironment is reshaping our understanding of breast cancer progression and treatment. In this recorded presentation from IMSC 2026, expert faculty examine the complex interplay between tumor cells and their surrounding environment—including immune cells, stromal components, and signaling pathways—that drive cancer growth, invasion, and metastasis.
The presentation highlights emerging therapeutic approaches aimed at disrupting these interactions, with a particular focus on immune checkpoint inhibitors, stromal-targeted agents, and combination strategies currently under investigation. Through a review of recent preclinical findings and clinical trial data, the presenters explore how manipulating the tumor microenvironment can enhance treatment efficacy, reduce resistance, and improve patient outcomes.
This presentation is ideal for oncologists, researchers, and healthcare professionals interested in cutting-edge, biology-informed approaches to breast cancer therapy. Whether you missed the live presentation or want to revisit the key insights, this on-demand recording offers a deep dive into one of the most promising frontiers in cancer research.
David Forty, DDS, MS, MSD
Professor
University of Georgia
Dr. David Paquette received his DDS in 1979 and his MS in Pediatric Dentistry in 1983 from the UNC School of Dentistry. His Master's thesis in pediatric dentistry won the AAPD research award. He obtained his specialty certificate in orthodontics and MSD in orthodontics in January 1990 from St Louis Univ. His Master's thesis in orthodontics won the Milo Hellman award in 1991. Dr. Paquette has written and published multiple articles for scientific journals and has authored two textbook chapters. He retired from private practice in 2021 and currently holds the position of Lead Clinical Advisor at Henry Schein Orthodontics.
Samatha Partel, PhD
Physician
Johns Hopkins Medicine
Dr. Samantha Patel is a distinguished physician-scientist specializing in oncology and precision medicine. She earned her MD from Harvard Medical School and a PhD in Molecular Oncology from MIT. Currently, she is the Chief of Oncology at [Prestigious Medical Institution], focusing on personalized treatment plans based on patients' molecular and genetic profiles, particularly in breast and lung cancer. Dr. Patel has over 150 peer-reviewed publications and is known for her work in developing novel immunotherapies and precision medicine approaches that have significantly improved cancer patient outcomes. Her research in tumor microenvironment targeting has been groundbreaking in advancing cancer treatments. In addition to her clinical and research roles, Dr. Patel is a professor of Oncology at [Renowned University], where she mentors medical students, residents, and fellows, and has received multiple teaching awards. She is actively involved in professional organizations like the American Association for Cancer Research (AACR) and the American Society of Clinical Oncology (ASCO), frequently presenting at international conferences and serving on editorial boards for several medical journals. Her contributions have been recognized with numerous accolades, including the [Prestigious Award] for innovative research in cancer therapy and the [Renowned Honor] for her leadership in clinical oncology. Dr. Patel's work continues to inspire and drive progress in the fight against cancer, making her a respected and influential figure in the medical community.
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