Session 1: Oncology Advances
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Moderator: David Johnson, PhD – Physician, Massachusetts General Hospital
Chair: Samantha Hayes, PhD – Associate Professor, Cornell University
Learning Objectives:
- Understand the latest developments and breakthroughs in oncology research, including emerging treatment modalities, novel therapeutic targets, and advancements in precision medicine.
- Explore the implications of recent oncology advances on clinical practice, patient outcomes, and quality of life, with a focus on personalized treatment approaches, survivorship care, and the integration of supportive services.
- Acquire practical knowledge and skills to enhance multidisciplinary collaboration and evidence-based decision-making in oncology care, fostering a comprehensive and patient-centered approach to cancer management.
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Contains 2 Component(s)
This presentation highlights recent advancements in immunotherapy for melanoma, focusing on novel treatment approaches and combination strategies. We discuss the mechanisms of action of immunotherapeutic agents, clinical trial data, and emerging biomarkers for predicting treatment response.
In recent years, immunotherapy has revolutionized the treatment landscape for melanoma, offering new hope for patients with advanced disease. This dynamic 30-minute presentation provides a comprehensive overview of the most recent developments in immunotherapeutic approaches for melanoma, with an emphasis on the clinical application of novel agents and combination therapies.
The presentation begins by examining the underlying mechanisms of action for key immunotherapeutic classes, including immune checkpoint inhibitors and T-cell-based therapies, and how these interventions engage the host immune system to target malignant cells. Speakers will present recent clinical trial findings that highlight improved outcomes and expanded indications for both first-line and refractory melanoma cases.
Additionally, the session explores combination strategies—such as pairing immunotherapy with targeted therapies, chemotherapy, or radiation—to overcome resistance and improve response durability. A focal point of the talk includes emerging biomarkers that are beginning to guide personalized treatment decisions, with a discussion on predictive and prognostic indicators under investigation.
Ideal for oncologists, researchers, and clinicians involved in melanoma care, this presentation offers evidence-based insights and practical considerations to help inform current treatment decisions and future research directions. Attendees will leave with a stronger understanding of how evolving immunotherapy strategies are shaping the future of melanoma management.
Samatha Partel, PhD
Physician
Johns Hopkins Medicine
Dr. Samantha Patel is a distinguished physician-scientist specializing in oncology and precision medicine. She earned her MD from Harvard Medical School and a PhD in Molecular Oncology from MIT. Currently, she is the Chief of Oncology at [Prestigious Medical Institution], focusing on personalized treatment plans based on patients' molecular and genetic profiles, particularly in breast and lung cancer. Dr. Patel has over 150 peer-reviewed publications and is known for her work in developing novel immunotherapies and precision medicine approaches that have significantly improved cancer patient outcomes. Her research in tumor microenvironment targeting has been groundbreaking in advancing cancer treatments. In addition to her clinical and research roles, Dr. Patel is a professor of Oncology at [Renowned University], where she mentors medical students, residents, and fellows, and has received multiple teaching awards. She is actively involved in professional organizations like the American Association for Cancer Research (AACR) and the American Society of Clinical Oncology (ASCO), frequently presenting at international conferences and serving on editorial boards for several medical journals. Her contributions have been recognized with numerous accolades, including the [Prestigious Award] for innovative research in cancer therapy and the [Renowned Honor] for her leadership in clinical oncology. Dr. Patel's work continues to inspire and drive progress in the fight against cancer, making her a respected and influential figure in the medical community.
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Contains 2 Component(s)
This presentation explores the role of the tumor microenvironment in breast cancer progression and metastasis. We discuss novel therapeutic strategies targeting the tumor microenvironment, including immune checkpoint inhibitors and stromal-targeted therapies, and their potential impact on patient outcomes.
Discover how the evolving science of the tumor microenvironment is reshaping our understanding of breast cancer progression and treatment. In this recorded presentation from IMSC 2026, expert faculty examine the complex interplay between tumor cells and their surrounding environment—including immune cells, stromal components, and signaling pathways—that drive cancer growth, invasion, and metastasis.
The presentation highlights emerging therapeutic approaches aimed at disrupting these interactions, with a particular focus on immune checkpoint inhibitors, stromal-targeted agents, and combination strategies currently under investigation. Through a review of recent preclinical findings and clinical trial data, the presenters explore how manipulating the tumor microenvironment can enhance treatment efficacy, reduce resistance, and improve patient outcomes.
This presentation is ideal for oncologists, researchers, and healthcare professionals interested in cutting-edge, biology-informed approaches to breast cancer therapy. Whether you missed the live presentation or want to revisit the key insights, this on-demand recording offers a deep dive into one of the most promising frontiers in cancer research.
David Forty, DDS, MS, MSD
Professor
University of Georgia
Dr. David Paquette received his DDS in 1979 and his MS in Pediatric Dentistry in 1983 from the UNC School of Dentistry. His Master's thesis in pediatric dentistry won the AAPD research award. He obtained his specialty certificate in orthodontics and MSD in orthodontics in January 1990 from St Louis Univ. His Master's thesis in orthodontics won the Milo Hellman award in 1991. Dr. Paquette has written and published multiple articles for scientific journals and has authored two textbook chapters. He retired from private practice in 2021 and currently holds the position of Lead Clinical Advisor at Henry Schein Orthodontics.
Samatha Partel, PhD
Physician
Johns Hopkins Medicine
Dr. Samantha Patel is a distinguished physician-scientist specializing in oncology and precision medicine. She earned her MD from Harvard Medical School and a PhD in Molecular Oncology from MIT. Currently, she is the Chief of Oncology at [Prestigious Medical Institution], focusing on personalized treatment plans based on patients' molecular and genetic profiles, particularly in breast and lung cancer. Dr. Patel has over 150 peer-reviewed publications and is known for her work in developing novel immunotherapies and precision medicine approaches that have significantly improved cancer patient outcomes. Her research in tumor microenvironment targeting has been groundbreaking in advancing cancer treatments. In addition to her clinical and research roles, Dr. Patel is a professor of Oncology at [Renowned University], where she mentors medical students, residents, and fellows, and has received multiple teaching awards. She is actively involved in professional organizations like the American Association for Cancer Research (AACR) and the American Society of Clinical Oncology (ASCO), frequently presenting at international conferences and serving on editorial boards for several medical journals. Her contributions have been recognized with numerous accolades, including the [Prestigious Award] for innovative research in cancer therapy and the [Renowned Honor] for her leadership in clinical oncology. Dr. Patel's work continues to inspire and drive progress in the fight against cancer, making her a respected and influential figure in the medical community.